Rabbit Secondary Antibodies
Biolegend Purified anti-AMD1
Purified anti-AMD1 [W18041A]; Isotype: Rat IgG2b, κ; Reactivity: Human; Apps: WB, IHC-P; Size: 25 μg
Biolegend Purified anti-AMD1
Purified anti-AMD1 [W18041A]; Isotype: Rat IgG2b, κ; Reactivity: Human; Apps: WB, IHC-P; Size: 100 μg
ABclonal Technology PE Rabbit anti-Mouse CD62E mAb
Predicted to enable several functions including oligosaccharide binding activity phospholipase binding activity and sialic acid binding activity Involved in positive regulation of leukocyte tethering or rolling Acts upstream of or within positive regulation of leukocyte migration Predicted to be located in several cellular components including caveola clathrin-coated pit and perinuclear region of cytoplasm Predicted to be integral component of plasma membrane Predicted to be active in external side of plasma membrane and extracellular space Is expressed in several structures including adrenal gland genitourinary system incisor integumental system and limb segment Human ortholog(s) of this gene implicated in IgA glomerulonephritis brain ischemia cerebrovascular disease and coronary artery disease Orthologous to human SELE (selectin E)
Abcam Rabbit Anti-Human IgG H&L.
Rabbit Anti-Human IgG H&L.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Rabbit Anti-Human IgG3 H&L (Biotin).
Rabbit Anti-Human IgG3 H&L (Biotin).
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology PE Rabbit anti-Human Siglec-8
Sialic acid-binding immunoglobulin (Ig)-like lectins or SIGLECs (e g CD33 (MIM 159590)) are a family of type 1 transmembrane proteins each having a unique expression pattern mostly in hemopoietic cells SIGLEC8 is a member of the CD33-like subgroup of SIGLECs which are localized to 19q13 3-q13 4 and have 2 conserved cytoplasmic tyrosine-based motifs an immunoreceptor tyrosine-based inhibitory motif or ITIM (see MIM 604964) and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM MIM 603492) that mediates an association with SLAM-associated protein (SAP MIM 300490) (summarized by Foussias et al 2000 [PubMed 11095983])
ABclonal Technology PE Rabbit anti-Human Siglec-8
Sialic acid-binding immunoglobulin (Ig)-like lectins or SIGLECs (e g CD33 (MIM 159590)) are a family of type 1 transmembrane proteins each having a unique expression pattern mostly in hemopoietic cells SIGLEC8 is a member of the CD33-like subgroup of SIGLECs which are localized to 19q13 3-q13 4 and have 2 conserved cytoplasmic tyrosine-based motifs an immunoreceptor tyrosine-based inhibitory motif or ITIM (see MIM 604964) and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM MIM 603492) that mediates an association with SLAM-associated protein (SAP MIM 300490) (summarized by Foussias et al 2000 [PubMed 11095983])
ABclonal Technology PE Rabbit anti-Human Siglec-8
Sialic acid-binding immunoglobulin (Ig)-like lectins or SIGLECs (e g CD33 (MIM 159590)) are a family of type 1 transmembrane proteins each having a unique expression pattern mostly in hemopoietic cells SIGLEC8 is a member of the CD33-like subgroup of SIGLECs which are localized to 19q13 3-q13 4 and have 2 conserved cytoplasmic tyrosine-based motifs an immunoreceptor tyrosine-based inhibitory motif or ITIM (see MIM 604964) and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM MIM 603492) that mediates an association with SLAM-associated protein (SAP MIM 300490) (summarized by Foussias et al 2000 [PubMed 11095983])
ABclonal Technology 594 Rabbit anti-Human CD46
The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I which protects the host cell from damage by complement In addition the encoded protein can act as a receptor for the Edmonston strain of measles virus human herpesvirus-6 and type IV pili of pathogenic Neisseria Finally the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome Alternatively spliced transcript variants encoding different isoforms have been described
ABclonal Technology PE Rabbit anti-Mouse CD25 mAb
Enables interleukin-2 binding activity and interleukin-2 receptor activity Acts upstream of or within several processes including Notch signaling pathway activation-induced cell death of T cells and regulation of T cell proliferation Located in external side of plasma membrane Is expressed in bone marrow Used to study Sjogren s syndrome and inflammatory bowel disease Human ortholog(s) of this gene implicated in immunodeficiency 41 lymphopenia multiple sclerosis type 1 diabetes mellitus and type 1 diabetes mellitus 10 Orthologous to human IL2RA (interleukin 2 receptor subunit alpha)
ABclonal Technology 450 Rabbit anti-Human CD45
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth differentiation mitosis and oncogenic transformation This PTP contains an extracellular domain a single transmembrane segment and two tandem intracytoplasmic catalytic domains and thus is classified as a receptor type PTP This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling It functions through either direct interaction with components of the antigen receptor complexes or by activating various Src family kinases required for the antigen receptor signaling This PTP also suppresses JAK kinases and thus functions as a regulator of cytokine receptor signaling Alternatively spliced transcripts variants of this gene which encode distinct isoforms have been reported
ABclonal Technology PE Rabbit anti-Human GPRC5D
The protein encoded by this gene is a member of the G protein-coupled receptor family however the specific function of this gene has not yet been determined
ABclonal Technology 594 Rabbit anti-Human CD131
The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3 IL-5 and CSF Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP)
ABclonal Technology 450 Rabbit anti-Human CD45
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth differentiation mitosis and oncogenic transformation This PTP contains an extracellular domain a single transmembrane segment and two tandem intracytoplasmic catalytic domains and thus is classified as a receptor type PTP This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling It functions through either direct interaction with components of the antigen receptor complexes or by activating various Src family kinases required for the antigen receptor signaling This PTP also suppresses JAK kinases and thus functions as a regulator of cytokine receptor signaling Alternatively spliced transcripts variants of this gene which encode distinct isoforms have been reported
ABclonal Technology PE Rabbit anti-Mouse CD44 mAb
This gene enables hyaluronic acid and type II TGF-beta receptor binding contributing to cytokine binding and receptor activity It regulates T cell activation protein phosphorylation and intracellular signaling Involved in Wnt signaling epithelium morphogenesis and wound healing it plays a role in inflammatory response Located in the basolateral plasma membrane external plasma membrane and microvilli it is part of the macrophage migration inhibitory factor receptor complex Expressed in various systems including alimentary branchial arch CNS genitourinary and limb Human orthologs are linked to breast carcinoma multiple carcinomas and prostate cancer It is orthologous to human CD44 a molecule in the Indian blood group